Collaboration
业务合作
Innovative Small Molecule Drugs
Henovcom has an experienced in-house team in pharmaceutical chemistry, pharmacology, pharmacodynamics, pharmacokinetics, toxicology and formulations, as well as global regulatory and clinical operation.
Hennovcom has established a molecular biology laboratory, cell culture room, animal laboratory, pre-prescription research laboratory, drug analysis laboratory, all operating under a robust research quality management system.
Multiple innovative drugs have progressed to the clinical stage, with DMFs of clofarabine and cladribine submitted to the US FDA.
Additionally, Henovcom operates a cGMP-like API pilot manufacturing workshop.
Innovative mRNA Capping Agent LZCap® & NTPs
The Henovcom team has extensive experience in antisense ODN, nucleoside, and nucleotide chemistry since the early 1990s. Two DMFs of nucleoside analog APIs, cladribine and clofarabine, have been submitted to the FDA. Henovcom has developed a competitive and scalable nucleotide triphosphate synthesis process platform and GMP compliant facility:
Nucleotides for mRNA therapeutics: Cap1 analogs as LZCap®AG, LZCap®AGm6AG, LZCap®AU, Biotin/Fam/Cy3/Cy5/Cy7 labeled LZCap®s, pUTP, 5OMeUTP, 5mCTP, m6ATP, modified nucleotides and NTPs.
Nucleotides for molecular in vitro diagnosis: fluorescent labeled dNTPs, Biotin labeled dNTPs, dNTPs.
Henovcom’s nucleotide products and services are delivered promptly while upholding the highest quality standards at competitive prices. We can supply hundreds kilograms of high-quality various nucleotide triphosphates annually, with customized synthesis services also offered.
In-house a state-of-the art GMP facility.
mRNA Therapeutics
Henovcom has established a comprehensive platform that encompasses the entire process of mRNA drug development. We offer a range of technical services, including mRNA sequence optimization, plasmid DNA construction, mRNA stock solution preparation and purification, LNP component synthesis and LNP mRNA encapsulation, cellular functional assay, animal testing and quality analysis of the entire process.
Henovcom has a highly skilled professional team with 11 Ph.D. scientists and 20 M.S. researchers. Each core members have extensive experience in the discovery and development of novel drugs. The company offers customers efficient, fast and personalized services in synthesis, drug molecular design, process development and other services related to new drug development.
1. Product delivery mode: Products and relevant data reports are delivered regularly in accordance with the technical service contract.
2. FTE mode: A dedicated independent R&D team is established for customer projects, providing regular progress reports on research and submitting product and data reports to customers.
Customized synthesis, drug molecular design, process development, drug evaluation, quality research, formulation process development.
The customer submits service requirements and provides relevant materials, following which both parties sign a confidentiality agreement.
Based on the specific conditions of the service project, both parties engage in negotiations regarding the contract duration,, expenses and other pertinent matters.
Upon reaching an agreement, Henovcom prepares the technical service contract.
The customer remits the deposit, and Henovcom commences project implementation.
Upon completion, Henovcom delivers products and relevant materials, and the customer settles the remaining balance.
